Neonatal Magnetic Resonance Imaging Pattern of Brain Injury as a Biomarker of Childhood Outcomes following a Trial of Hypothermia for Neonatal Hypoxic-Ischemic Encephalopathy.

Authors: 
S. Shankaran; S.A. McDonald; A.R. Laptook; S.R. Hintz; P.D. Barnes; A. Das; A. Pappas; R.D. Higgins; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network
Abstract: 

OBJECTIVE: To examine the ability of magnetic resonance imaging (MRI) patterns of neonatal brain injury defined by the National Institute of Child Health and Human Development Neonatal Research Network to predict death or IQ at 6-7 years of age following hypothermia for neonatal encephalopathy.

STUDY DESIGN: Out of 208 participants, 124 had MRI and primary outcome (death or IQ

Citation: 

Shankaran S, McDonald SA, Laptook AR, et al. "Neonatal Magnetic Resonance Imaging Pattern of Brain Injury as a Biomarker of Childhood Outcomes following a Trial of Hypothermia for Neonatal Hypoxic-Ischemic Encephalopathy." J Pediatr. 2015;167(5):987-93.e3.PubMed

Publication type: 
Journal Article
Year: 
2015
CPQCC publication: 
Yes
PubMed ID: 
26387012
PMCID: 
PMC4700815