28 NICUs participating in a quality improvement collaborative targeting early-onset sepsis antibiotic use.

Authors: 
K.S.E. Payton; M.V. Bennett; J. Schulman; W.E. Benitz; L. Stellwagen; G.L. Darmstadt; J. Quinn; A.I. Kristensen-Cabrera; C.C. Breault; M. Bolaris; L. Lefrak; J. Merrill; P.J. Sharek
Abstract: 

OBJECTIVE: There is widespread overuse of antibiotics in neonatal intensive care units (NICUs). The objective of this study was to safely reduce antibiotic use in participating NICUs by targeting early-onset sepsis (EOS) management.

STUDY DESIGN: Twenty-eight NICUs participated in this statewide multicenter antibiotic stewardship quality improvement collaborative. The primary aim was to reduce the total monthly mean antibiotic utilization rate (AUR) by 25% in participant NICUs.

RESULT: Aggregate AUR was reduced by 15.3% (p 

Citation: 

Payton KSE, Bennett MV, Schulman J, et al. "28 NICUs participating in a quality improvement collaborative targeting early-onset sepsis antibiotic use." J Perinatol. 2024.PubMed

Publication type: 
Journal Article
Year: 
2024
CPQCC publication: 
Yes
PubMed ID: 
38378826
PMCID: 
7848759