Behavior Profiles at 2 Years for Children Born Extremely Preterm with Bronchopulmonary Dysplasia.

Authors:

J.E. Brumbaugh; E.F. Bell; S.F. Grey; S.B. DeMauro; B.R. Vohr; H.M. Harmon; C.M. Bann; M.A. Rysavy; W. Logan; T.T. Colaizy; M.A. Peralta-Carcelen; E.C. McGowan; A.F. Duncan; B.J. Stoll; A. Das; S.R. Hintz; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network

Abstract:

OBJECTIVE: To characterize behavior of 2-year-old children based on the severity of bronchopulmonary dysplasia (BPD).

STUDY DESIGN: We studied children born at 22-26 weeks of gestation and assessed at 22-26 months of corrected age with the Child Behavior Checklist (CBCL). BPD was classified by the level of respiratory support at 36 weeks of postmenstrual age. CBCL syndrome scales were the primary outcomes. The relationship between BPD grade and behavior was evaluated, adjusting for perinatal confounders. Mediation analysis was performed to evaluate whether cognitive, language, or motor skills mediated the effect of BPD grade on behavior.

RESULTS: Of 2310 children, 1208 (52%) had no BPD, 806 (35%) had grade 1 BPD, 177 (8%) had grade 2 BPD, and 119 (5%) had grade 3 BPD. Withdrawn behavior (P

Citation:

Brumbaugh JE, Bell EF, Grey SF, et al. "Behavior Profiles at 2 Years for Children Born Extremely Preterm with Bronchopulmonary Dysplasia." J Pediatr. 2020;219:152-159.e5.PubMed

Publication type:

Journal Article

Year:

2020

CPQCC publication:

Yes

PubMed ID:

32008764

PMCID:

PMC7096270