Neuroimaging and neurodevelopmental outcome in extremely preterm infants.

Authors:

S.R. Hintz; P.D. Barnes; D. Bulas; T.L. Slovis; N.N. Finer; L.A. Wrage; A. Das; J.E. Tyson; D.K. Stevenson; W.A. Carlo; M.C. Walsh; A.R. Laptook; B.A. Yoder; K.P. Van Meurs; R.G. Faix; W. Rich; N.S. Newman; H. Cheng; R.J. Heyne; B.R. Vohr; M.J. Acarregui; Y.E. Vaucher; A. Pappas; M. Peralta-Carcelen; D.E. Wilson-Costello; P.W. Evans; R.F. Goldstein; G.J. Myers; B.B. Poindexter; E.C. McGowan; I. Adams-Chapman; J. Fuller; R.D. Higgins; SUPPORT Study Group of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network

Abstract:

BACKGROUND: Extremely preterm infants are at risk for neurodevelopmental impairment (NDI). Early cranial ultrasound (CUS) is usual practice, but near-term brain MRI has been reported to better predict outcomes. We prospectively evaluated MRI white matter abnormality (WMA) and cerebellar lesions, and serial CUS adverse findings as predictors of outcomes at 18 to 22 months' corrected age.

METHODS: Early and late CUS, and brain MRI were read by masked central readers, in a large cohort (n = 480) of infants

Citation:

Hintz SR, Barnes PD, Bulas D, et al. "Neuroimaging and neurodevelopmental outcome in extremely preterm infants." Pediatrics. 2015;135(1):e32-42.PubMed

Publication type:

Journal Article

Year:

2015

CPQCC publication:

Yes

PubMed ID:

25554820

PMCID:

PMC4279063